Protease Inhibitors and Phosphatase Inhibitors
Medchemexpress LLC Z-VRPR-FMK TFA | 1381885-28-4 | 95.9% | 790.81 | 500 UG
Z-VRPR-FMK (TFA), also known as VRPR, is a tetrapeptide that functions as a selective and irreversible inhibitor of MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1). It can also protect against influenza A virus (IAV) infection.
- Functions as a selective and irreversible MALT1 inhibitor.
- Protects against influenza A virus (IAV) infection.
Cayman Chemical ENPP1 InhIbItr C asy Reage 1ea
ENPP1 Inhibitor C Assay Reagent has been tested and formulated to work exclusively with Cayman’s ENPP1 Fluorescent Inhibitor Screening Assay Kit (Item No.702090).
![Medchemexpress LLC 3-[(2-pyridinyl)methylene]indolin-2-one | 3367-88-2 | 99.1% | 222.24 | C14H10N2O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239575.png-250.jpg)
Medchemexpress LLC 3-[(2-pyridinyl)methylene]indolin-2-one | 3367-88-2 | 99.1% | 222.24 | C14H10N2O | 10MG
(E/Z)-GSK-3β inhibitor 1 (CAS 3367-88-2) is a small-molecule research compound that inhibits glycogen synthase kinase-3 beta. Supplied as an orange to red solid, it has molecular formula C14H10N2O and a molecular weight of approximately 222.24 g·mol-1. The material is provided at high purity for biochemical and cell-based research and should be stored protected from light and handled as a research chemical.
- Inhibits glycogen synthase kinase-3 beta in biochemical assays.
- Supplied as an orange to red solid for laboratory use.
- High purity suitable for research applications.
- Available in small quantities appropriate for experimental workflows.
- Store protected from light; in solvent store at -80°C for long term and -20°C for short term.
Cayman Chemical MAGL InhIbItr Compound 23 50mg
An inhibitor of MAGL (IC50 = 80 nM); selective for MAGL over CB1, CB2, FAAH, ABHD6, and ABHD12 (IC50s = >10 μM); inhibits the growth of HCT116, MDA-MB-231, Caov-3, OVCAR-3, and SKOV3 cells (IC50s = 21, 7.9, 25, 57, and 15 μM, respectively) but not MRC5 cells (IC50 = >100 μM); increases the levels of 2-AG in mouse brain and plasma at 50 mg/kg
Selleck Chemical LLC JNJ-7706621 5mg 443797-96-4
JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6 in cell-free assays. It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Nintedanib (BIBF 1120) 5mg 656247-17-5 Intedanib, Vargatef, Ofev
Nintedanib (BIBF 1120, Intedanib, Vargatef, Ofev) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFR?/? with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Echelon Biosciences Research Labs SS14 Tumor Inhibitor Analog - 0.5 mg,
SS14 Tumor Inhibitor Analog - 0.5mg , D-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2 Category/Application: Neuropeptides Hormones This item is non returnable
Cayman Chemical Aurora KInase InhIbItr III 1mg
A potent inhibitor of Aurora A kinase (IC50 = 42 nM); selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively)
CPC Scientific DABCYL-GABA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Glu(EDANS)-Ala-Lys-NH2 (trifluoroacetate salt) 1MG
Selective fluorogenic matrix metalloproteinase (MMP) substrate with the following Kcat/Km value for MMP-3 (Stromelysiin-1) is 29.0 M-1s-1, for MMP-13 13.0 M-1s-1, and for MMP-9 7.5 M-1s-1 (at pH = 7.5, 25°C). The fluorescence increase is measured using an wavelength of 360 nm and an emission wavelength of 490 nm. No activity against this substrate could be measured with MMP-1, MMP-7, and MMP-8. ONE-LETTER SEQUENCE: Dabcyl-GABA-RPKPVE-Nva-WR-Glu(EDANS)-AK-NH2MOLECULAR FORMULA: C99H144N28O20S1MOLECULAR WEIGHT:2078.44STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [202273-56-1], RESEARCH AREA: CancerREFERENCES: Beekman, B., et al., 1997. FEBS Lett 418, 305.
Cayman Chemical IRAK InhIbItr 1 10mg
An IRAK4 inhibitor (IC50 = 35 nM); selective for IRAK4 over JNK1 and JNK2 at 10 µM; prevents increases in TNF-α and IL-12p40 levels in M. bovis-infected THP-1 cells at 1 µM
CPC Scientific DNP-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(Nma)-NH2 (trifluoroacetate salt) 1MG
SEQUENCE: DNP-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(Nma)-NH2 (trifluoroacetate salt)ONE-LETTER SEQUENCE: Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2MOLECULAR FORMULA: C51H12N14O12S1MOLECULAR WEIGHT: 1105.29STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [150956-93-7]SYNONYMS: Dnp-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NHRESEARCH AREA: CancerREFERENCES:SKU(s): MMPS-005A, MMPS-005B
Selleck Chemical LLC PHA-665752 5mg 477575-56-7
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9 nM in cell-free assays, >50-fold selectivity for c-Met than RTKs or STKs. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Echelon Biosciences Research Labs Caspase 1 Substrate - 5 mg,
Caspase 1 Substrate - 5mg , Ac-Trp-Glu-Ala-Asp-pNA Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Caspase 3 Substrate - 5 mg,
Caspase 3 Substrate - 5mg , Ac-Asp-Glu-Val-Asp-4-methoxy-2-naphthylamide Category/Application: Enzyme Substrates This item is non returnable
Echelon Biosciences Research Labs Granzyme B Substrate - 0.5 mg,
Granzyme B Substrate - 0.5mg , Ac-Ile-Glu-Pro-Asp-AFC Category/Application: Enzyme Substrates This item is non returnable